Varenicline

• Varenicline tartrate is a highly-selective nicotinic acetylcholine receptor (nAChR) agonist
• Varenicline solution nasal spray (VNS), brand name Tyrvaya^®, was approved by the FDA in 2021 for the treatment of the signs and symptoms of dry eye disease

TYRVAYA is a registered trademark of Oyster Point Pharma, Inc., a Viatris Company.
TYRVAYA^® (varenicline solution) nasal spray. Prescribing Information. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/213978s005lbl.pdf.